Latest research on degenerative cervical myelopathy

8 papers · updated 2026-09-26 · Spine · All topics

The newest papers on degenerative cervical myelopathy from the orthopaedic journals The Reduction reads, newest first, each with a one-line summary. The list is drawn from the digest’s archive and refreshed every week.

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Recent papers

  1. ACDF vs PCDF vs Laminoplasty for Multilevel Cervical Myelopathy: A Systematic Review and Meta-Analysis.

    Spine · Sep 21 2026 · PubMed

    This meta-analysis found ACDF, PCDF, and laminoplasty yield similar neurological recovery for multilevel cervical myelopathy, but differ in pain, motion, hospital stay, and complications—guiding approach selection.

  2. Predictors of Residual Neck/Shoulder Symptom Following Surgery for Degenerative Cervical Myelopathy: A Multicenter Prospective Cohort Study.

    Spine · Sep 01 2026 · PubMed

    In this cohort, 68% of patients had persistent neck/shoulder symptoms 2 years after DCM surgery, with female sex, longer symptom duration, and higher preoperative VAS score predicting persistence.

  3. Impact of Preoperative Intramedullary T2 Signal Intensity Changes on Surgical Outcomes in Cervical Spondylotic Myelopathy: A Multicenter Prospective Study.

    Spine · Aug 12 2026 · PubMed

    In this multicenter study of 721 CSM patients, preoperative T2 signal intensity on MRI did not independently predict worse 2-year neurological or patient-reported outcomes after adjusting for confounders.

  4. Cervical myelopathy responses to extracts derived from combustible cigarettes and heated tobacco products: in vivo and in vitro evidence.

    Journal of Neurosurgery: Spine · Jul 31 2026 · PubMed

    In rat and cell models, extracts from both combustible cigarettes and heated tobacco products worsened motor/sensory deficits and neuronal damage in cervical myelopathy, suggesting HTPs are not a safer alternative for these patients.

  5. Complication Profiles of Corpectomy-Containing Versus Non-Corpectomy Anterior Cervical Surgery for Degenerative Cervical Myelopathy: A Multicenter Study of 1,024 Cases.

    Spine · Jul 20 2026 · PubMed

    Corpectomy-containing anterior cervical procedures showed higher perioperative morbidity than non-corpectomy procedures for myelopathy; much of difference reflects ossified posterior longitudinal ligament pathology.

  6. Preoperative metabolite ratio improves prediction of postoperative recovery in degenerative cervical myelopathy: a prospective cohort study.

    The Spine Journal · Jul 16 2026 · PubMed

    In a prospective cohort with cervical myelopathy, adding preoperative MRS metabolite ratios (Cho/NAA, Cr/NAA, MIn/NAA) to clinical/imaging data substantially improved prediction of postoperative neurological recovery (AUC up to 0.92).

  7. Diagnosis and Management of Degenerative Cervical Myelopathy.

    Journal of the American Academy of Orthopaedic Surgeons · Dec 15 2025 · Review · PubMed

    This review outlines evolving diagnosis and surgical management of degenerative cervical myelopathy, favoring earlier surgical intervention and highlighting shifts from laminectomy toward laminoplasty/fusion and disk arthroplasty to reduce complications.

  8. Failure of Surgical Equipoise in Posterior Cord Syndrome Myelopathy.

    JAAOS Global Research & Reviews · Dec 01 2023 · Review · PubMed

    Two cases show posterior cord syndrome in cervical spondylotic myelopathy failed anterior decompression but responded to posterior decompression, suggesting posterior approach should be considered when this syndrome is clinically diagnosed.

Landmark papers

  1. Radiculopathy and Myelopathy at Segments Adjacent to the Site of a Previous Anterior Cervical Arthrodesis*

    Journal of Bone and Joint Surgery (American) · 1999 · cited 1,674 times · PubMed

    Symptomatic adjacent-segment disease occurs in 25.6% of patients within 10 years after single anterior cervical arthrodesis, particularly at C5-C6 and C6-C7 levels with preexisting degeneration.

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