Flexor tendon healing in vitro: Effects of TGF-β on tendon cell collagen production

J Hand Surg Am · 2002 · Classic · cited 271 times

Matthew B. Klein, Naveen Yalamanchi, Hung Pham, Michael T. Longaker, James Chan

Division of Plastic and Hand Surgery, Stanford University Medical Center, Stanford

Hand & Upper Extremity

SUMMARY — THE REDUCTIONIn rabbit flexor tendon cell cultures, TGF-beta isoforms 1, 2, and 3 significantly increased collagen I and III production, suggesting that modulating TGF-beta could help control adhesion formation.

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