Flexor Tendon Adhesion Formation: Current Concepts.

Hand Clin · May 2023 · Review

Kuroiwa T, Amadio PC

Department of Orthopedic Surgery, Mayo Clinic, 200 First St. SW

Hand & Upper Extremity

SUMMARY — THE REDUCTIONDespite advances in antiadhesion technologies, no method perfectly inhibits flexor tendon adhesions while maintaining repair strength; emerging biomaterials show promise in animal models.
Abstract, as published

Over the years, various physical and chemical/biological methods of inhibiting adhesion formation have been developed, focusing on how to suppress healing around the tendon and not inhibit healing within the tendon. Unfortunately, however, these methods are accompanied by drawbacks, both large and small, and no absolute antiadhesion method capable of maintaining tendon repair strength has yet been developed. Recent innovations in biomaterials science and tissue engineering have produced new antiadhesion technologies, such as barriers combined with cytokines and cells, which have improved outcomes in animal models, and which may find clinical relevance in the future.

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