Current perspectives on peripheral nerve repair and management of the nerve gap.

J Hand Surg Eur Vol · Jun 2024 · Review

McMorrow LA, Czarnecki P, Reid AJ, Tos P

Blond McIndoe Laboratories, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, UK

Hand & Upper Extremity

SUMMARY — THE REDUCTIONReviews modern peripheral nerve repair options—including autografts, nerve transfers, conduits, and acellular allografts—summarizing current evidence for managing nerve gaps.
Abstract, as published

From the first surgical repair of a nerve in the 6th century, progress in the field of peripheral nerve surgery has marched on; at first slowly but today at great pace. Whether performing primary neurorrhaphy or managing multiple large nerve defects, the modern nerve surgeon has an extensive range of tools, techniques and choices available to them. Continuous innovation in surgical equipment and technique has enabled the maturation of autografting as a gold standard for reconstruction and welcomed the era of nerve transfer techniques all while bioengineers have continued to add to our armamentarium with implantable devices, such as conduits and acellular allografts. We provide the reader a concise and up-to-date summary of the techniques available to them, and the evidence base for their use when managing nerve transection including current use and applicability of nerve transfer procedures.

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