Nerve Autograft: Preservation of a Lost Art.

Hand Clin · Aug 2024 · Review

Wu RT, Chuieng-Yi Lu J

Division of Reconstructive Microsurgery, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial…

Hand & Upper Extremity

SUMMARY — THE REDUCTIONReview of nerve autografts, which remain the gold standard for bridging nerve gaps by offering biocompatibility and a regeneration scaffold, despite donor site morbidity and added operative time.
Abstract, as published

Nerve autografts involve the transplantation of a segment of the patient's own nerve to bridge a nerve gap. Autografts provide biological compatibility, support for axonal regeneration, and the ability to provide an anatomic scaffold for regrowth that other modalities may not match. Disadvantages of the autograft include donor site morbidity and the extra operative time needed to harvest the graft. Nevertheless, nerve autografts such as the sural nerve remain the gold standard in reconstructing nerve gaps, but a multitude of factors need to be favorable in order to garner reliable, consistent outcomes.

Featured in the 2026-10-05 issue.

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