The Benefits of Awake Spinal Surgery on Minimizing Positioning-related Complications: A Narrative Review.

Spine (Phila Pa 1976) · Apr 15 2025 · Review

Assis MLM, Bojaxhi E, Abode-Iyamah KO, Patterson JS, White KE, Gruenbaum SE, et al.

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Jacksonville, FL

Spine

SUMMARY — THE REDUCTIONThis narrative review suggests awake lumbar spine surgery under neuraxial anesthesia may reduce prone-positioning complications (vision loss, nerve injury, pressure ulcers) and improve hemodynamic stability compared with general anesthesia.
Abstract, as published

OBJECTIVE: This review examines the potential advantages of awake spinal surgery under neuroaxial anesthesia in minimizing positioning-related complications compared with traditional general anesthesia.

SUMMARY OF BACKGROUND DATA: Spinal surgeries performed in the prone position under general anesthesia are associated with perioperative complications, such as ocular injury and vision loss, nerve damage, and pressure ulcers.

MATERIALS AND METHODS: A comprehensive literature search was conducted for articles published from 1986 to 2023 focusing on awake spinal surgery and positioning-related complications. In addition, insights from the Mayo Clinic team were incorporated to assess the potential benefits of awake spine surgery.

RESULTS: The review identified several positioning-related complications associated with prone positioning during spine surgery, including perioperative visual loss, neuropathies, pressure ulcers, and intra-abdominal hypertension leading to systemic cardiovascular effects and potential organ dysfunction. Advances at the Mayo Clinic have enabled the use of awake spinal surgery under neuroaxial anesthesia for complex procedures such as robotic transforaminal lumbar interbody fusion. The use of awake lumbar spine surgery has demonstrated advantages, including reduced positioning-related complications, immediate patient feedback to avoid harmful maneuvers, shorter operating room times, and improved hemodynamic stability.

CONCLUSIONS: Awake lumbar spine surgery offers notable advantages in reducing positioning-related complications and presents a promising alternative to general anesthesia.

STUDY DESIGN: Literature review and institutional analysis.

Featured in the 2026-10-17 issue.

← Understanding the minimum clinically important difference: a …Comorbidity-Specific Risk of Revision Following Single-Level … →

The Reduction is a free email digest of newly published orthopaedic literature — a handful of new papers in the subspecialties you choose, each summarized like this one. Subscribe free or browse the archive.