Approach to Femoral Shaft Nonunions: Diagnosis and Management.

J Am Acad Orthop Surg · Dec 01 2025 · Review

Wellings EP, Blair JA

From the Department of Orthopedic Surgery, Mayo Clinic, Jacksonville, GA (Blair)

Orthopaedic Trauma

SUMMARY — THE REDUCTIONThis review outlines evidence-based diagnostic workup and management strategies for femoral shaft nonunions, which occur in 2–6% of cases despite high union rates with IM nailing.
Abstract, as published

Despite the high union rate of femoral shaft fractures treated with intramedullary nailing (90% to 100%), the annual incidence of femoral shaft nonunion ranges from 2% to 6%. Although less common than tibial nonunions, femoral shaft nonunions remain a clinical problem in orthopaedic surgery. Proper treatment begins with appropriate diagnosis, workup, and identification of risk factors followed by a multidisciplinary approach to treatment. This article provides current evidence-based guidance for providers on the diagnosis and management of femoral shaft nonunions.

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