Pulmonary Function in Early-Onset Scoliosis: A Literature Review.

JBJS Rev · Sep 01 2025 · Review

Manning AE, Redding G, Bauer J, Yaszay B, Yang S

Seattle Children's Hospital, Seattle, Washington

Spine

SUMMARY — THE REDUCTIONThis review finds that growth-friendly surgery for early-onset scoliosis improves radiographic outcomes but does not reliably restore normal pulmonary function, calling for better combined outcome measures.
Abstract, as published

» Early-onset scoliosis (EOS) causes restrictive lung disease, secondary to deformation of the thoracic cavity, stiffening of the chest wall, and weakening of the respiratory muscles.» Early spinal fusion has been shown to limit thoracic growth and be associated with poor pulmonary outcomes. This has led to the rise of growth-friendly surgical techniques to maximize thoracic growth.» Radiographic improvements occur, but lung functions do not predictably improve in proportion to normal growth after growth-friendly spine surgery for EOS.» Outcome measures in combination with lung function tests should be explored to better define the impact of EOS and its treatments.

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