Post-endoscopy subarachnoid hypertension syndrome: a case series in the recovery period after unilateral biportal endoscopic surgery under general anesthesia.

Eur Spine J · Sep 25 2026 · Recent

Zhang L, Wang Z, Guo X, Yang G, Chen D, Liu C

Department of Anesthesiology, Peking University Shenzhen Hospital, Shenzhen, China

Spine

SUMMARY — THE REDUCTIONThree patients developed acute severe hypertension, tachycardia, and altered consciousness after endoscopic spine surgery under general anesthesia; early recognition and supportive management led to full recovery within hours.
Abstract, as published

PURPOSE: To describe the clinical features, perioperative management, and outcomes of post-endoscopy subarachnoid hypertension syndrome (PESHS) in patients recovering from unilateral biportal endoscopic (UBE) spinal surgery under general anesthesia.

METHODS: This retrospective case series reviewed three consecutive patients who developed PESHS in the post-anesthesia care unit (PACU) following UBE procedures under general anesthesia at a single center.

RESULTS: The three patients presented with acute severe hypertension, tachycardia, altered consciousness, and increased muscle tone. Management included dehydration, sedation with propofol plus dexmedetomidine, analgesia, and anti-inflammatory therapy. Clinical improvement occurred within 2-5 h; all patients were discharged without sequelae.

CONCLUSION: PESHS after UBE is manageable with early recognition and a structured approach combining vigilant monitoring, targeted interventions, and meticulous nursing care.

Featured in the 2026-10-04 issue.

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