Latest research on open fractures

8 papers · updated 2026-11-02 · Orthopaedic Trauma · All topics

The newest papers on open fractures from the orthopaedic journals The Reduction reads, newest first, each with a one-line summary. The list is drawn from the digest’s archive and refreshed every week.

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Recent papers

  1. Efficacy of Pull-In Suture for Tendon Avulsion Injury Associated With Severe Forearm Open Fracture, Forearm Amputation, and Hand Amputation.

    HAND · Oct 08 2026 · PubMed

    In 10 patients with severe forearm trauma or amputations from industrial machinery, the pull-in suture for musculotendinous avulsions gave fair hand function (DASH 28.7), a viable option when other primary repairs aren't feasible.

  2. Optimizing the Disinfection of Devitalized Bone for Retained Use in Open Fractures: An in vitro Study.

    Journal of Orthopaedic Trauma · Aug 01 2026 · PubMed

    Chlorohexidine achieved complete bacterial disinfection of contaminated cortical bone without affecting mechanical properties; autoclave was effective but reduced strength.

  3. Management of Open Fractures of the Extremities and Pediatrics.

    Journal of the American Academy of Orthopaedic Surgeons · Oct 01 2024 · Review · PubMed

    This review updates current evidence and controversies on antibiotic timing, surgical timing, and flap coverage in managing open extremity fractures in adults and children.

  4. Advances in Soft Tissue Injuries Associated with Open Fractures.

    Hand Clinics · Nov 2023 · Review · PubMed

    This review addresses soft tissue management in open upper extremity fractures, covering fixation, negative pressure wound therapy, dermal regenerative templates, and local and free tissue options for hand reconstruction.

  5. Open fractures of the upper limb - do the BOAST guidelines need an update?

    Injury · Jun 2023 · Review · PubMed

    This scoping review finds that open upper limb fractures have lower infection rates than lower limb injuries, suggesting BOAST timing could be relaxed in selected cases, though early antibiotics and debridement within 24 hours remain key.

  6. Prevention of infection in open fractures: Where are the pendulums now?

    Injury · May 2020 · Review · PubMed

    Review of open fracture infection prevention supports early thorough debridement with saline irrigation, early wound closure/coverage, and systemic plus local antibiotics; VAC shows no infection benefit, while rhBMP-2 may help in type III tibial fractures.

  7. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations.

    Journal of the American Academy of Orthopaedic Surgeons · Apr 15 2020 · Review · PubMed

    Reviews the evolution of prophylactic antibiotics for open fractures guided by Gustilo-Anderson type, noting that duration and drug choice remain unstandardized and coverage of resistant organisms is unresolved.

  8. Wound Irrigation for Open Fractures.

    JBJS Reviews · Jan 2020 · Review · PubMed

    This review of open fracture wound irrigation finds normal saline to be the optimal agent, with pressure and pulsatile lavage not affecting outcomes, while ideal timing and volume still need clinical trials.

Landmark papers

  1. Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones

    Journal of Bone and Joint Surgery (American) · 1976 · cited 3,275 times

    A structured protocol of debridement, culture-guided closure, and prophylactic antibiotics dramatically reduced infection rates in open long bone fractures, including severe Type III injuries.

  2. Prevention of Infection in the Treatment of One Thousand and Twenty-Five Open Fractures of Long Bones

    Journal of Bone and Joint Surgery (American) · 2002 · cited 2,810 times · PubMed

    A prophylactic protocol combining debridement, staged closure, and perioperative antibiotics dramatically reduced infection rates in over 1,000 open long bone fractures, even in severe Type III injuries.

  3. Negative Pressure Wound Therapy After Severe Open Fractures: A Prospective Randomized Study

    Journal of Orthopaedic Trauma · 2009 · cited 349 times · PubMed

    In a randomized trial, negative pressure wound therapy after severe open fractures cut deep infection rates roughly fivefold compared to standard gauze dressings.

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