Oct 19–25, 2026 · 8 new studies, 5 reviews · Orthopaedic Oncology archive · All weeks
The new Orthopaedic Oncology research The Reduction sent the week of Oct 19–25, 2026, with the week’s most recent reviews, each with a one-line summary.
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In 27 patients, DCE-MRI showed spinal osteosarcoma metastases are hypervascular, and plasma volume fell about 46% after radiation, suggesting perfusion imaging could noninvasively track treatment response.
In 101 surgical patients with metastatic spinal cord compression, unsupervised clustering identified four preoperative phenotypes; chronic, severe deficit with sensory loss predicted the poorest motor recovery, which may help guide counseling.
In 72 patients, postembolization CT-DSA only moderately agreed with catheter angiography, and residual tumor enhancement was not significantly associated with surgical blood loss, so its predictive value needs further validation.
In 30 patients, a custom 3D-printed arthrodesis prosthesis after proximal humerus tumor resection gave 100% fusion and good function (MSTS 84%), but total deltoidectomy raised soft-tissue failure risk.
Narrative review adapting the NOMS framework to cervical spine tumors, emphasizing junctional instability, systemic fitness, and multidisciplinary planning, with surgery mainly for decompression, stabilization, and diagnosis alongside radiation and systemic therapy.
In 134 retroperitoneal sarcoma resections, incisional hernia occurred in about 34% regardless of incision type, so combined incisions for oncologic exposure did not add hernia risk.
Meta-analysis of 23 studies found about 17% instrumentation failure after total en bloc spondylectomy, rising with longer follow-up, plus 44% complications and 2.7% mortality, supporting at least five years of radiographic surveillance.
Using four cases and a narrative review, this paper outlines surgical decision-making for en bloc resection of primary malignant subaxial cervical spine tumors, emphasizing planning, multistage approaches, and alternatives when en bloc resection is not feasible.
Contemporary Management of Standard Chordoma Arising in the Mobile Spine and Sacrum.
Chordoma management centers on en bloc resection with negative margins, yet late recurrence reaches up to 50%; advanced radiation (SBRT, proton, carbon ion) increasingly serves as adjuvant or standalone therapy within a multidisciplinary approach.
Socioeconomic disparities in musculoskeletal oncology.
Reviews socioeconomic and insurance-related disparities across musculoskeletal oncology, spanning metastatic bone disease, hematologic malignancies, primary bone cancers, and soft tissue sarcomas.
Extra-skeletal osteosarcoma: a review.
This review of rare extra-skeletal osteosarcoma covers its demographics, presentation, imaging, differential diagnosis (including myositis ossificans), management, and outcomes as a reference for clinicians caring for soft tissue tumors.
Review of genomic, proteomic, and immunologic biomarkers in soft tissue sarcoma, and their potential to improve diagnosis, prognosis, and prediction of recurrence and treatment response.
Musculoskeletal Effects of Antineoplastic Agents.
Reviews musculoskeletal adverse effects of common chemotherapy and targeted agents such as taxanes, helping orthopaedic surgeons recognize treatment-related complaints in the growing population of cancer survivors.
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