This week in Spine

Sep 14–20, 2026 · 24 new studies, 10 reviews · Spine archive · All weeks

The new Spine research The Reduction sent the week of Sep 14–20, 2026, with the week’s most recent reviews, each with a one-line summary.

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New research

  1. Comparison of liposomal bupivacaine and modified cocktail analgesia for postoperative pain control after transforaminal lumbar interbody fusion: a prospective, double-blind, randomized controlled trial.

    Journal of Neurosurgery: Spine · Sep 18 2026 · PubMed

    In a RCT of 118 TLIF patients, liposomal bupivacaine via ESPB cut opioid/PCA use more than a cheaper modified analgesic cocktail, though both controlled early pain well.

  2. Beyond Anatomical Resectability: A Hypermetabolic and Highly Aggressive Subtype of Spinal Chordoma Associated with Cancer-Specific Progression.

    The Spine Journal · Sep 18 2026 · PubMed

    In 36 spinal chordoma patients, PET/CT-derived metabolic burden plus SINS>10 and Enneking stage IIB identified a hypermetabolic, aggressive subtype with high risk of recurrence, metastasis, or death, enabling a preoperative risk score.

  3. Utilizing Robotic-Assisted Navigation in Early Onset Scoliosis: Experience From a Multicenter Registry.

    Journal of Pediatric Orthopaedics · Sep 16 2026 · PubMed

    Multicenter registry study finds robotic-assisted navigation achieves 97% accurate pedicle screw placement in early onset scoliosis surgery, though technical challenges like registration and calibration issues were common.

  4. Surgical Outcome of Modified Woodward Procedure in Congenital Undescended Scapula.

    Journal of Pediatric Orthopaedics · Sep 15 2026 · PubMed

    Modified Woodward procedure for Sprengel deformity produced significant gains in shoulder motion, scapular position, and patient-reported function, even in older children and those with scoliosis.

  5. Multifaceted infection prevention protocol is associated with reduced surgical site infection after spinal fusion: a before-and-after study.

    The Spine Journal · Sep 12 2026 · PubMed

    A bundled infection-prevention protocol (nasal decolonization, chlorhexidine bathing, glycemic control, aseptic reinforcement) cut surgical site infections after spinal fusion from 2.9% to 0.4%.

  6. Incidental Cervical Spine Stenosis by Race and Ethnicity Among Trauma Patients: A Retrospective Cross-sectional Clinical Study.

    The Spine Journal · Sep 11 2026 · PubMed

    In a trauma cohort, congenital cervical stenosis was more prevalent among Black patients than White patients, most commonly at C3-C4 rather than the traditionally reported C5 level.

  7. Development and validation of an AI framework for automated vertebral bone quality assessment of lumbar MRI.

    Journal of Neurosurgery: Spine · Sep 11 2026 · PubMed

    An automated AI pipeline for measuring vertebral bone quality on lumbar MRI correlated well with manual review and improved sensitivity for detecting DXA-defined osteoporosis at an optimized threshold.

  8. Trends in Vertebral Augmentation in South Korea (2010-2024): A Nationwide Population-Based Study With International Comparison.

    The Spine Journal · Sep 11 2026 · PubMed

    South Korean national data (2010-2024) show vertebroplasty use steadily rising—especially among patients 80 and older—diverging from the US shift toward kyphoplasty after sham-trial evidence.

  9. Incidence and Time Course of Adjacent Segment Disease After Anterior Cervical Fusion: A Multimodal Assessment in 400 Patients.

    Spine · Sep 10 2026 · PubMed

    In 400 patients after anterior cervical fusion, radiographic adjacent segment changes were common (35%) but clinically significant disease and reoperation were rare (~2-3%), showing a staged progression over time.

  10. Allogenic Red Blood Cell Transfusion Increases Risk of Overall Infection After Surgery for Spinal Metastasis: A Retrospective Multi-Institutional Cohort Study of 796 Patients.

    Spine · Sep 07 2026 · PubMed

    In 796 spinal metastasis surgery patients, allogenic RBC transfusion was independently and dose-dependently associated with higher 30-day infection risk with no safe transfusion threshold identified, supporting restrictive transfusion strategies.

  11. Paraspinal Muscle Quality and Functional Outcome After Lumbar Spinal Stenosis Surgery.

    Spine · Sep 07 2026 · PubMed

    In 344 lumbar spinal stenosis surgery patients, greater preoperative multifidus fatty infiltration—but not psoas size—predicted worse two-year disability outcomes and lower odds of meaningful improvement.

  12. Optimization is a Moving Target: A Continuous Modifiable Frailty Index (o-ASD-FI) Reflecting Optimization Prior to Complex Adult Spinal Deformity (ASD) Intervention.

    Spine · Sep 07 2026 · PubMed

    This study develops a modifiable frailty index (o-ASD-FI) for adult spinal deformity surgery that incorporates treatable comorbidities and independently predicts longer stay, complications, and worse outcomes, potentially improving preoperative risk stratification.

  13. Nerve and Tendon Transfers After Cervical Spinal Cord Injury: A Systematic Review of Strength Outcomes in 959 Patients.

    Journal of Hand Surgery (Global Online) · Sep 03 2026 · PubMed

    This systematic review of 959 patients found nerve and tendon transfers both restore useful strength after cervical spinal cord injury, though brachialis-to-AIN nerve transfer outcomes were notably poor, guiding procedure selection.

  14. Spinal Epidural Lipomatosis: Are Its Prevalence and Severity Increasing.

    Clinical Spine Surgery · Sep 03 2026 · PubMed

    Over a decade, spinal epidural lipomatosis prevalence in lumbar decompression patients rose significantly, with smoking and higher BMI linked to greater severity, implicating modifiable risk factors.

  15. Analysis of Commercially Negotiated Hospital Prices for Spinal Deformity Surgery in the United States.

    The Spine Journal · Sep 01 2026 · PubMed

    Analysis of over 6,000 hospital contracts shows negotiated prices for spinal deformity surgery vary widely, driven mainly by hospital system affiliation, size, labor costs, and market competition rather than clinical factors.

  16. Predictors of Residual Neck/Shoulder Symptom Following Surgery for Degenerative Cervical Myelopathy: A Multicenter Prospective Cohort Study.

    Spine · Sep 01 2026 · PubMed

    In this cohort, 68% of patients had persistent neck/shoulder symptoms 2 years after DCM surgery, with female sex, longer symptom duration, and higher preoperative VAS score predicting persistence.

  17. Role of a Novel, Fresh-Frozen Cellular Bone Allograft in Lumbar Interbody Spinal Fusion: A Retrospective, Matched-Cohort Study.

    Clinical Spine Surgery · Aug 31 2026 · PubMed

    In a matched cohort of 100 lumbar fusion patients, adding a cellular bone allograft to rhBMP-2 did not improve fusion rates or pain but significantly raised blood loss and cost.

  18. Combining universal access with high precision for revolutionary osteoporosis screening: CT-based 3D-HU volumetric bone density.

    Journal of Neurosurgery: Spine · Aug 28 2026 · PubMed

    A novel 3D Hounsfield unit method using routine CT scans matched QCT's accuracy for diagnosing osteoporosis and osteopenia, enabling opportunistic screening without extra cost or radiation.

  19. Do outcomes diverge over time? A 5-year Spine CORe™ Quality Outcomes Database study comparing patient-reported outcomes after minimally invasive versus open surgery for degenerative grade 1 lumbar spondylolisthesis.

    Journal of Neurosurgery: Spine · Aug 28 2026 · PubMed

    In this 5-year multicenter study, MIS and open surgery for grade 1 spondylolisthesis showed similar early outcomes, but MIS produced greater and more durable ODI improvement by 24 and 60 months, especially with fusion.

  20. Safety of Combined Anterior and Posterior Fusion in the Elderly Population.

    Spine · Aug 25 2026 · PubMed

    In propensity-matched patients, combined anterior-posterior lumbar fusion had similar complication rates in those ≥70 and <70 years old, supporting age not being a strict contraindication.

  21. Early Postoperative Increase in Procollagen Type 1 N-Propeptide (P1NP) Predicts One-Year Pseudarthrosis Following Anterior Cervical Discectomy and Fusion: A Prospective Cohort Study.

    Spine · Aug 25 2026 · PubMed

    A larger early postoperative rise in P1NP (a bone formation marker) independently predicted one-year pseudarthrosis after ACDF, suggesting a potential role for anabolic therapy trials in high-risk patients.

  22. A comprehensive framework for planning pedicle screw trajectory using ANTs template-based registration approach.

    European Spine Journal · Aug 24 2026 · PubMed

    An ANTs template-based registration framework predicted lumbar pedicle screw entry/target points with reasonable geometric accuracy, supporting automated patient-specific preoperative planning.

  23. Fully navigated biportal endoscopic lumbar decompression using non-invasive surface registration: a single-institution technical feasibility series.

    European Spine Journal · Aug 24 2026 · PubMed

    A feasibility series of 7 patients shows fully navigated biportal endoscopic lumbar decompression using non-invasive surface registration is safe and reproducible, with no registration failures or complications.

  24. Radiologic and Clinical Importance of Lamina Hinge Fractures After Open-Door Cervical Laminoplasty: A Propensity Score-Matched Study.

    Clinical Spine Surgery · May 01 2026 · PubMed

    Hinge fractures after open-door laminoplasty were more common in men with larger preoperative C2 SVA and led to early neck pain and kyphotic change, though most fractures healed by one year.

Recent reviews

  1. Osteoporosis and adult spinal deformity-a review for spinal surgeons by the SRS adult spinal deformity task force on senescence.

    Spine Deformity · Sep 2026 · PubMed

    SRS task force review synthesizes current knowledge on osteoporosis diagnosis, surgical risk, and non-operative/operative management in adult spinal deformity surgery.

  2. A scoping review of published reviews on the use of bracing in scoliosis.

    Spine Deformity · Jul 2026 · PubMed

    This scoping review of 59 studies confirms bracing reduces curve progression and surgery rates in AIS with adherence as key, but finds the evidence base largely low-quality and identifies gaps for future research.

  3. A call to arms: the absence of standardized return to play guidelines for professional rugby union players after cervical spine surgery.

    The Bone & Joint Journal · Mar 01 2026 · PubMed

    This review highlights the lack of standardized, evidence-based return-to-play protocols after cervical spine surgery in elite rugby union, calling for a multidisciplinary, sport-specific guideline to improve player safety.

  4. Clinical outcomes, safety, and cost considerations of rhBMP-2 in the surgical management of pyogenic spinal infections: a focused review.

    European Spine Journal · Oct 2025 · PubMed

    This review of 346 patients across six retrospective studies found rhBMP-2 use in surgery for pyogenic spinal infections achieved high fusion rates (~98%) and low reinfection (1.5%), supporting its selective use pending prospective trials.

  5. Improving Patient Outcomes by Reducing Anemia and Bleeding in Pediatric Spine Surgery.

    Journal of the American Academy of Orthopaedic Surgeons · Jun 05 2025 · PubMed

    This review argues that multidisciplinary patient blood management, blood conservation techniques, and ERAS protocols can reduce perioperative anemia and transfusion needs in pediatric spine surgery.

  6. Institution-Based Quality and Safety Improvement Initiatives in Spine Surgery: A Scoping Review.

    JBJS Reviews · May 01 2025 · PubMed

    This scoping review of 133 studies maps institution-based quality improvement initiatives in spine surgery, finding most focus on efficiency and safety but lack long-term outcome data.

  7. The Application of Artificial Intelligence in Spine Surgery: A Scoping Review.

    JAAOS Global Research & Reviews · Apr 01 2025 · PubMed

    This scoping review of 105 studies (2020-2024) found AI in spine surgery is mostly used for prognostication and diagnosis via supervised/deep learning, though most data are single-center and small-scale.

  8. Cauda Equina Syndrome: A Review of Classification, Diagnosis, Treatment, and Best Practices.

    JBJS Reviews · Feb 01 2025 · PubMed

    This JBJS review covers cauda equina syndrome's epidemiology, diagnosis, and debated decompression timing, while highlighting the significant legal risk tied to delayed diagnosis.

  9. Preserving privacy in big data research: the role of federated learning in spine surgery.

    European Spine Journal · Nov 2024 · PubMed

    Federated learning enables decentralized, privacy-preserving machine learning across institutions and shows promise for predictive modeling, telesurgery, and image segmentation in spine surgery.

  10. Isolated C1 arch fractures: C1-2 fusion vs. C1 osteosynthesis - surgical strategies for potentially unstable injuries.

    European Spine Journal · Oct 2024 · PubMed

    Literature review finds C1 osteosynthesis for isolated C1 arch fractures with transverse ligament rupture offers good fusion, deformity correction, and motion preservation compared with C1-2 fusion, though stronger evidence is needed.

← Week of Sep 7–13, 2026

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