This week in Orthopaedic Oncology

Jul 6–12, 2026 · 3 new studies, 1 review · Orthopaedic Oncology archive · All weeks

The new Orthopaedic Oncology research The Reduction sent the week of Jul 6–12, 2026, with the week’s most recent reviews, each with a one-line summary.

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New research

  1. Timing of Vascular Endothelial Growth Factor Inhibitor Reinitiation and Risk of Wound Complications in Spinal Metastasis Surgery.

    Journal of Bone and Joint Surgery (American) · Sep 02 2026 · PubMed

    Postoperative vascular endothelial growth factor inhibitor reintiation after 40 days reduced wound complications in spinal metastasis surgery compared with earlier resumption.

  2. Single-cell fixed RNA profiling of the osteosarcoma clinical Spectrum identifies ADAMTS12 and RNASE1 as key drivers of the metastatic niche.

    Journal of Bone Oncology · Aug 2026 · PubMed

    Single-cell transcriptomics identifies ADAMTS12 and RNASE1 as key drivers of osteosarcoma metastatic progression through malignant and immune cell signaling networks.

  3. Is Dose Reduction After Initial Treatment With Denosumab Associated With Subsequent Skeletal-related Events, Osteonecrosis of the Jaw, or Osteoporotic Fractures in Patients With Metastatic Carcinoma? A Nationwide Retrospective Comparative Study.

    Clinical Orthopaedics and Related Research · Jul 07 2026 · PubMed

    Lower denosumab doses reduced skeletal-related events risk while decreasing osteonecrosis of the jaw risk in metastatic cancer patients, suggesting dose reduction may optimize the benefit-harm profile.

Recent reviews

  1. Benign Bone Tumors of the Hand: Beyond Enchondromas.

    Journal of the American Academy of Orthopaedic Surgeons · Nov 01 2024 · PubMed

    Beyond enchondromas, hand surgeons should recognize benign bone tumors including osteogenic lesions, giant cell tumor, fibrous dysplasia, and unique entities like Nora lesions requiring distinct management approaches.

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